COLO-FC: Barriers to Faecal Immunochemical Test (FIT) completion amongst patients with symptoms of possible colorectal cancer

This study seeks to understand why some people may not complete a poo test, that looks for traces of blood, after going to the GP with symptoms of possible bowel cancer. By understanding what problems people experience, and whether there are particular groups of patients who experience these, we can work to develop strategies to support people to complete this test.

Colorectal Cancer Cohort Study

COLO-COHORT aims to develop a “risk stratification tool” to help determine which patients are at highest risk of having polyps or cancer; this tool will be able to be used in the future to work out which patients need to be referred to endoscopy for investigation.

Optimal Faecal Immunochemical Testing in Suspected Colorectal Cancer

COLOFIT examined how GPs should use a new test, Faecal Immunochemical Test (FIT), to identify which patients with bowel symptoms, are at higher risk of bowel cancer and need to be examined in hospital.

A Randomised Controlled Trial of Lesion Detection at Colonoscopy Using the GI Genius™ Artificial Intelligence Platform

COLO-DETECT is a randomised control trial which evaluated whether colonoscopy assisted with the GI Genius™ Intelligent Endoscopy Module improves the detection of abnormalities such as polyps and cancer compared to standard colonoscopy.

COLOrectal Symptoms after PelvIc RadIoTherapy

COLO-SPIRIT is a study that investigated the burden, experiences and management of radiation proctopathy (RP) among cancer survivors, in order to inform the development of a trial of PuraStat© (a synthetic material that aims to control bleeding) as a treatment for RP.

A validated Patient Reported Experience Measure for Gastrointestinal Endoscopy

Our main study aim is to develop a tool which measures patient experience (patient reported experience measure, PREM) of gastrointestinal procedures, including colonoscopy. We will then translate the PREM so that it can be used internationally, to help identify areas of these procedures which can be targeted to improve patient experience. It will also be used in clinical trials to compare interventions.

Obesity Related Colorectal Adenoma Risk Study

The OSCAR study is a prospective multi-centre cross sectional study which looked at the association between obesity, Non-alcoholic Fatty Liver Disease (NAFLD) and colorectal adenomas.

Volatile Organic compounds for DEtection of Colorectal cAncer

The VODECA study aimed to investigate Volatile Organic Compounds (VOCs) which are associated with adenomas (pre-cancerous polyps) and early bowel cancer to improve detection of adenomas and bowel.

Study of Prevention by Aspirin and EPA; Knowledge of Mechanism of Action

The STOP-ADENOMA study followed on from a completed clinical trial called seAFOod, in which we tested whether aspirin and the omega-3 EPA, alone or together, prevent bowel polyps (which are known to progress to cancer if left unchecked).